Cross-Sectional Study of Anti-Tuberculosis Treatment Adherence Levels Under the DOTS Strategy at Betung Kota Community Health Center, Indonesia

Agung Palendra; Yovi  Pranata; Rahayu Wijayanti

Authors

Agung Palendra Study Program of Pharmacy, Universitas Kader Bangsa Palembang, Palembang, South Sumatra, Indonesia
Yovi Pranata Study Program of Pharmacy, Universitas Kader Bangsa Palembang, Palembang, South Sumatra, Indonesia
Rahayu Wijayanti Study Program of Pharmacy, Universitas Kader Bangsa Palembang, Palembang, South Sumatra, Indonesia

Keywords:

Adherence, DOTS, Knowledge, Tuberculosis, Questionnaire

Abstract

Tuberculosis (TB) is an infectious disease that requires a high level of adherence to Anti-Tuberculosis Drugs (OAT), particularly through the implementation of the Directly Observed Treatment Short-Course (DOTS) strategy. This study aims to analyze the level of medication adherence to OAT based on the DOTS strategy at Betung Kota Community Health Center, Indonesia. This research employed an analytical quantitative method with a cross-sectional design, involving TB patients (35 respondents) who had undergone treatment for at least one month, selected using purposive sampling. Data were collected using structured questionnaires and analyzed using univariate and bivariate methods with the chi-square test. The results showed that the majority of patients had a good level of knowledge (82.9%) and a high level of treatment adherence (85.7%), in accordance with treatment success standards. The implementation of the DOTS strategy was considered quite optimal, as reflected by regular patient visits, the active role of treatment supervisors (PMO), and the availability of OAT. Statistical analysis indicated a significant relationship between the level of knowledge and medication adherence (p = 0.003), suggesting that better knowledge contributes to higher adherence to TB therapy. In conclusion, the DOTS strategy plays an important role in improving adherence to OAT among TB patients. Strengthening patient education, family support, and continuous monitoring is essential to maintain treatment success.

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